Jimmy Fallon (The Tonight Show Starring Jimmy Fallon (2014)) and Dwayne Johnson (Furious Seven (2015)) go head-to-head.

Common and John Legend go head-to-head.

Anne Hathaway and Emily Blunt go head-to-head.

Anna Kendrick and John Krasinski go head-to-head.

Mike Tyson takes on Terry Crews.

Michael Strahan and Hoda Kotb face off.

Comic and writer Stephen Merchant goes head-to-head with actress Malin Akerman.

Professional dancer Derek Hough goes face-to-face with his sister, professional dancer Julianne Hough.

Hip-hop-group mates Cheryl 'Salt' James and Pepa face off.

Actress and rapper Queen Latifah goes head-to-head with actor Marlon Wayans.

Actress Alison Brie faces off against actor Will Arnett.

Justin Bieber goes head-to-head with Deion Sanders.

Andy Cohen goes head-to-head with Willie Geist.

Victoria Justice goes head-to-head with Gregg Sulkin.

Broad City (2014) co-stars Abbi Jacobson and Ilana Glazer go head-to-head.

Celebrity couple Iggy Azalea and Nick Young face off.

Part 1. Empire (2015) co-stars Terrence Howard and Taraji P. Henson go head-to-head.

Part 2. Empire (2015) co-stars Taraji P. Henson and Terrence Howard go head-to-head.

The Night Before (2015) co-stars Seth Rogen, Joseph Gordon-Levitt and Anthony Mackie go head-to-head.